BMEN5031: Engineering Extracellular Matrices

This class explores the complex set of fibrous and linking proteins of tissues, namely the extracellular matrix (ECM). The ECM is crucial not only for maintaining the structure of tissues but also for guiding and maintaining cellular functions and fate processes. The purpose of the course is to become acquainted with ECM proteins and to investigate how control or manipulation of ECM proteins impacts on cell and tissue function with an emphasis on impacts for regenerative medicine. In the course of this study, we will apply fundamentals of physics, chemistry, and mathematics to make predictions, solve problems and optimize outcomes related to ECM engineering. Required prerequisites: Upper Division Undergraduate or Graduate level student standing in CSE. Recommended prerequisites: BMEn 2501, 3011/3015, 3111/3115, 3311/3315, or equivalents (introductory cell/molecular biology, biomaterials, biotransport, biomechanics).

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