Structure of biological macromolecules that are targets of drugs. Techniques to accelerate directed drug discovery. Protein structure/interactions. Popular target classes. Computational tools for visualizing/analyzing protein-ligand and protein-protein interactions. Structural characterization at a level sufficient to underpin critical data evaluation. Biophysical techniques to assess weak ligand binding and suitable for fragment-based lead discovery.
prereq: 5710 or 8002 or CHEM 5412 or structural biochemistry or instr consent
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