Infections caused by microbes significantly impact global health. This course explores the principles of anti-infective drugs through their mechanisms of action on the biology of microbial life cycles and infections. Different modules of the course will cover viruses, bacteria, fungi, and protozoa, with a focus on discussing the features of these microbial pathogens that are exploited for pharmacological targets. Students will explore the pharmacological principles behind major drug classes and their mechanisms for targeting pathogens. The course will examine the cellular and molecular basis of drug action, efficacy, limitations, resistance, and current challenges. Each module will also include the discussion of a recent research paper, allowing students to apply the principles learned in that module to explore emerging topics in the development of novel anti-infective drugs. By understanding the principles and mechanisms of anti-infective drugs, students will gain a solid foundation in current medicines used for treating infectious diseases and a strong basis for building further knowledge on the application and development of novel anti-infective agents.
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